Bibliographie (2546)
Study: Lateral flow antigen testing can rapidly and accurately detect early COVID-19 among patients presenting with flu-like illness and can be a plausible alternative to RT-PCR.
lundi, 26 juillet 2021 09:29 Écrit par Zouhair SouissiComparing the diagnostic accuracy of point-of-care lateral flow antigen testing for SARS-CoV-2 with RT-PCR in primary care (REAP-2) – EClinicalMedicine News release: Lateral flow tests are 95% effective at detecting Covid-19 when used at the onset of symptoms – University of Oxford Related: Interactive Infographic | Interpreting a lateral flow SARS-CoV-2 antigen test – “This […]
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![[Preprint] RCT: In patients with COVID-19 and severe hypoxia, dexamethasone 12 mg did NOT result in statistically significant improved outcomes compared to dexamethasone 6 mg – “Mortality at 28 days was 27.1% and 32.3% in patients assigned to 12 mg and 6](/media/k2/items/cache/306600c868fe6b67afe34e9f7a9f98b7_L.jpg)
[Preprint] RCT: In patients with COVID-19 and severe hypoxia, dexamethasone 12 mg did NOT result in statistically significant improved outcomes compared to dexamethasone 6 mg – “Mortality at 28 days was 27.1% and 32.3% in patients assigned to 12 mg and 6
lundi, 26 juillet 2021 09:29 Écrit par Zouhair SouissiDexamethasone 12 mg versus 6 mg for patients with COVID-19 and severe hypoxia: an international, randomized, blinded trial – medRxiv
The post [Preprint] RCT: In patients with COVID-19 and severe hypoxia, dexamethasone 12 mg did NOT result in statistically significant improved outcomes compared to dexamethasone 6 mg – “Mortality at 28 days was 27.1% and 32.3% in patients assigned to 12 mg and 6 mg, respectively (adjusted relative risk 0.86, 99% CI, 0.68-1.08)”. appeared first on Links Medicus.
Large cohort study finds one in two hospitalized COVID-19 patients develop a complication.
lundi, 26 juillet 2021 09:29 Écrit par Zouhair SouissiCharacterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study – The Lancet Commentaries: Landmark study finds one in two hospitalised COVID-19 patients develop a complication – National Institute for Health Research In-hospital complications associated with COVID-19 – The Lancet CV Complications Common in Hospitalized […]
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Position paper: Advancing precision medicine for acute respiratory distress syndrome.
lundi, 26 juillet 2021 04:44 Écrit par Zouhair SouissiAdvancing precision medicine for acute respiratory distress syndrome – The Lancet Respiratory Medicine Related: Review: Personalized mechanical ventilation in acute respiratory distress syndrome. Seminar | Acute respiratory distress syndrome. M-A of randomized trials: In patients with acute respiratory distress syndrome, there was no difference in mortality between higher vs. lower positive end-expiratory pressure strategies. M-A: […]
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Review: Ethics in extracorporeal life support.
vendredi, 23 juillet 2021 14:00 Écrit par Zouhair SouissiEthics in extracorporeal life support: a narrative review – Critical Care
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How the Delta variant achieves its ultrafast spread – “Viral load is roughly 1,000 times higher in people infected with the Delta variant than those infected with the original coronavirus strain, according to a study in China”.
vendredi, 23 juillet 2021 14:00 Écrit par Zouhair SouissiHow the Delta variant achieves its ultrafast spread – Nature Original study: Study shows the viral loads in the Delta infections are ~1000 times higher than those in the earlier strain infections on the day when viruses are firstly detected.
The post How the Delta variant achieves its ultrafast spread – “Viral load is roughly 1,000 times higher in people infected with the Delta variant than those infected with the original coronavirus strain, according to a study in China”. appeared first on Links Medicus.
What are the Delta, Gamma, Beta and Alpha Covid variants?
vendredi, 23 juillet 2021 14:00 Écrit par Zouhair SouissiRelated: Increased transmissibility and global spread of SARS-CoV-2 variants of concern – “Estimated transmissibility increases of alpha 29% (95% CI: 24–33), beta 25% (95% CI: 20–30), gamma 38% (95% CI: 29–48) & delta 97% (95% CI: 76–117)”. AND WHO renames COVID-19 variants with the Greek alphabet (i.e., Alpha, Beta, Gamma, etc), making them simple, easy […]
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Opinion | Tocilizumab in COVID-19 therapy: who benefits, and how? – the researchers suggest that maybe IL-6 inhibitors should be given only to patients with high IL-6.
vendredi, 23 juillet 2021 14:00 Écrit par Zouhair SouissiTocilizumab in COVID-19 therapy: who benefits, and how? – The Lancet Related: A living WHO guideline on drugs for covid-19 – interleukin-6 receptor blockers are now recommended for patients with severe or critical covid-19. AND M-A: Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19 – “The 4% absolute risk reduction […]
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Review: Personalized mechanical ventilation in acute respiratory distress syndrome.
jeudi, 22 juillet 2021 14:00 Écrit par Zouhair SouissiPersonalized mechanical ventilation in acute respiratory distress syndrome – Critical Care Related: M-A of randomized trials: In patients with acute respiratory distress syndrome, there was no difference in mortality between higher vs. lower positive end-expiratory pressure strategies. AND Seminar | Acute respiratory distress syndrome. AND Short review: Diagnosis and management of acute respiratory distress syndrome […]
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COVID-19 antibodies persist at least nine months after infection – “98.8 percent of people infected in February/March showed detectable levels of antibodies in November”.
jeudi, 22 juillet 2021 14:00 Écrit par Zouhair SouissiNews release: COVID-19 antibodies persist at least nine months after infection – Imperial College London Original study: SARS-CoV-2 antibody dynamics and transmission from community-wide serological testing in the Italian municipality of Vo’ – Nature Communications
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