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5 versus 14 days of prednisone for acute COPD exacerbations

In this multicentre, double-blind, randomised control trial, a shorter 5-day course of glucocorticoids was compared with a 14-day course to assess non-inferiority. Patients received an initial dose of IV methylprednisone, then 4 days of oral prednisone, followed by further prednisone or a placebo.

This study confirms that further steroids seem neither to do more harm nor more good...

Author: Laura J Quint
Source:Thorax 69:868 doi:10.1136/thoraxjnl-2013-204439
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