The epithelial‐to‐mesenchymal transition (EMT) is a developmental program that regulates embryonic morphogenesis and involves significant morphological and molecular changes in cells. Experimental models have revealed that EMT also contributes to various malignant features of cancer cells, including motile, invasive, anti‐apoptotic and stem‐like phenotypes.

Clinically, correlative studies have indicated that mesencymal‐like features of tumor cells are associated with poor tumor differentiation as well as worse patient prognosis. Nevertheless, due to its transitory nature, demonstration of an actual occurrence of EMT during human carcinogenesis is challenging, and most of the evidence to date has been limited to breast and colorectal cancers. However, recent studies sugges...