Effectiveness of mRNA BNT162b2 COVID-19 vaccine up to 6 months in a large integrated health system in the USA: a retrospective cohort study – The Lancet Commentary: Expert reaction to study on Pfizer-BioNTech vaccine effectiveness up to 6 months – Science Media Centre Commentary on Twitter Study of 3.4 million people @aboutKP @TheLancet Vaccine […]
The post Cohort study: Pfizer vaccine effectiveness against any infections declined from 88% during the first month after full vaccination to 47% after 5 months. Vaccine effectiveness against hospital admissions remained high; 87% within 1 month, and 88% at 5 months after full vaccination, with no significant waning. appeared first on Links Medicus.
Effect of Convalescent Plasma on Organ Support–Free Days in Critically Ill Patients With COVID-19 A Randomized Clinical Trial – JAMA Commentary: Convalescent plasma futile as treatment for critically ill COVID-19 patients, study finds – University of Pittsburgh Related: RCT: Convalescent plasma does not improve outcomes and may be harmful to hospitalized patients with COVID-19. NIH […]
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Will the pandemic fade into an ordinary disease like the flu? The world is watching Denmark for clues – Science
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Covid-19 vaccination: evidence of waning immunity is overstated – The BMJ Related: COVID vaccine immunity is waning — how much does that matter? – “As debates about booster shots heat up, what’s known about the duration of vaccine-based immunity is still evolving”. COVID vaccine effects wane over time but still prevent death and severe illness. […]
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Summary: Does testing for cancer in people with unprovoked blood clots in the legs and lungs reduce cancer- and blood clot-related death and illness? – Cochrane Library Original article: Effect of testing for cancer on cancer‐ or venous thromboembolism (VTE)‐related mortality and morbidity in people with unprovoked VTE – Cochrane Library
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Merck and Ridgeback’s Investigational Oral Antiviral Molnupiravir Reduced the Risk of Hospitalization or Death by Approximately 50 Percent Compared to Placebo for Patients with Mild or Moderate COVID-19 in Positive Interim Analysis of Phase 3 Study Commentaries: Expert reaction to interim analysis of oral antiviral molnupiravir – Science Media Centre Merck’s antiviral pill reduces hospitalization […]
The post [Press release – not published yet] Merck announces oral antiviral Molnupiravir reduced the risk of hospitalization or death by approximately 50 Percent compared to placebo for patients with mild or moderate COVID-19. appeared first on Links Medicus.
Vaccine induced immune thrombocytopenia and thrombosis: summary of NICE guidance – The BMJ Original Guidance: NICE COVID-19 rapid guideline: vaccine-induced immune thrombocytopenia and thrombosis. Related: Clinical features of vaccine-induced immune thrombocytopenia and thrombosis. Review: Clinical characteristics and pharmacological management of COVID-19 vaccine–induced immune thrombotic thrombocytopenia with cerebral venous sinus thrombosis. Vaccine-induced immune thrombotic thrombocytopenia: what […]
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A Systematic Review and a Meta-Analysis Comparing Prophylactic and Therapeutic Low Molecular Weight Heparins for Mortality Reduction in 32,688 COVID-19 Patients – Frontiers in Pharmacology Related: M-A: Safety and efficacy of different prophylactic anticoagulation dosing regimens in critically and non-critically ill patients with COVID-19 – According to this analysis, standard-dose prophylactic anticoagulation should be the […]
The post Another meta-analysis suggests standard-dose prophylactic anticoagulation is the best option for patients hospitalized with Covid-19. appeared first on Links Medicus.
Transition to endemicity: Understanding COVID-19 – Cell Related: COVID will likely shift from pandemic to endemic — but what does that mean? Perspective | How Endemic COVID Becomes a Manageable Risk – “Businesses and schools must adapt, because the dual threat from the coronavirus and the flu will be too severe”.
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COVID-19 in older adults – Cleveland Clinic Journal of Medicine
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