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Obesity hypoventilation syndrome: From sleep‐disordered breathing to systemic comorbidities and the need to offer combined treatment strategies

ABSTRACTObesity hypoventilation syndrome (OHS) is defined as a combination of obesity (body mass index ≥ 30 kg/m2), daytime hypercapnia (partial arterial carbon dioxide concentration ≥45 mm Hg) and sleep‐disordered breathing after ruling out other disorders that may cause alveolar hypoventilation. Through the prism of the International Classification of Functioning, OHS is a chronic condition associated with respiratory, metabolic, hormonal and cardiovascular impairments, leading to a decrease in daily life activities, a lack of social participation and high risk of hospitalization and death. Despite its severity, OHS is largely underdiagnosed and the health‐related costs are higher than those of apnoeic or obese eucapnic patients. The present review discusses the definit...

Correlation between circulating fibrocytes, and activity and progression of interstitial lung diseases

Conclusions:  The results from this study provide further evidence for the role of circulating fibrocytes in fibrotic lung diseases. (Source: Respirology)

Comparison of adherence between twice‐ and thrice‐daily regimens of oral amoxicillin/clavulanic acid

Conclusions:  The rate of compliance with amoxicillin/clavulanic acid therapy was very low. However, compliance with the new formulation that is taken twice‐daily was significantly better. (Source: Respirology)

Treatments for anxiety and depression in patients with chronic obstructive pulmonary disease: A literature review

ABSTRACTChronic obstructive pulmonary disease (COPD) is a serious contemporary health issue. Psychological co‐morbidities such as anxiety and depression are common in COPD. Current evidence for treatment options to reduce anxiety and depression in patients with COPD was examined. There is evidence available for the efficacy of pharmacological treatments, cognitive behavioural therapy, pulmonary rehabilitation, relaxation therapy and palliative care in COPD. Therapeutic modalities that have not been proven effective in decreasing anxiety and depression in COPD, but which have theoretical potential among patients, include interpersonal psychotherapy, self‐management programmes, more extensive disease management programmes, supportive therapy and self‐help groups. Besides pulmonary reha...

Radiofrequency ablation could extend survival for inoperable lung cancer

Percutaneous pulmonary radiofrequency ablation - a non-invasive intervention that kills lung tumors with heat - appears to offer 2 years of survival for most patients with primary and metastatic lung cancer, researchers claim.

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